Stay One Step Ahead of Your Competition! You got stronger when Ed Byrd introduced creatine in 1993. Now you get bigger with his NO2: NO2 was created by the same man who introduced creatine to the market in 1993 - Ed Byrd, co-founder of EAS and now president of Medical Research Institute - MRI. NO2 has created a revolutionary new category of muscle-builders and muscle-enhancers known as 'cell-signaling hemodilators. Through mediation of the "signaling-molecule" nitric oxide (NO), NO2 induces powerful hemodilation and creates dramatic increases in muscle size, strength, endurance, power output, and load capacity. With its advanced sustained-release technology "pHyser3", NO2 generates a virtual permanent muscle pump, now known as the "perpetual pump."